Universitaetsklinikum Hamburg-Eppendorf (UKE)- DE

hamburg-eppendorfGeneral description:

The University Medical Center Hamburg-Eppendorf (UKE) is one of the most modern hospitals in Europe with more than 80 highly specialized clinics and research institutes. The largest among Hamburg’s hospitals with approximately 1.400 hospital beds, the medical center treats each year around 50.000 in-patients. Additionally, approximately 250.000 out-patients as well as 50.000 emergency patients are treatedThe UKE represents a combination of state-of-the-art medical treatment, research, science and education with international reputation. The focus of many UKE institutes is within the network selected by the German Council of Science and Humanities focusing on molecular imaging research and inflammatory disease such as the metabolic syndrome. The participating Department of Biochemistry and Molecular Cell Biology has a long standing expertise in basic and translational lipid research. The existing cooperation with CAN, the Department of Chemistry and the Department of Radiology enable the utilization of a broad range of analytical platforms including nanoparticle-based multimodal imaging.

Website:

http://www.uke.de/

Expertise:

The understanding of molecular mechanisms causing abnormalities in lipid and lipoprotein metabolism, which are associated with the development of chronic inflammatory disorders such as atherosclerosis and the metabolic syndrome.

Facilities:

Mouse models; validated cell cultures for white (mouse, human) and brown (mouse) adipocytes, nanoparticle based lipid tracing technology, 7-Tesla magnetic resonance imaging system for rodents, confocal intravital imaging, high-throughput lipid and lipoprotein profiling platform.

Other EU Projects:

CureHLH (European initiative to improve knowledge, treatment and survival of haemophagocytic syndromes in children, FP7-HEALTH-201461); T3Net (Tissue transmigration training network, FP7-PEOPLE-237946); MULTISENSE (The merging of the senses: understanding multisensory experience, ERC Advanced Grant-269716); DISSECT (Disseminating tumor cells as novel biomarkers: Dissecting the metastatic cascade in cancer patients, FP7-IDEAS – ERC Advanced Grant Interdisciplinary Panel-269081); DEM-CHILD (A Treatment-Oriented Research Project of NCL Disorders as a Major Cause of Dementia in Childhood, FP7-HEALTH-281234); EuRhythDia (Chronotherapeutic lifestyle intervention for diabetes and obesity to reset the circadian rhythm and improve cardiometabolic risk in the European working population – FP7-HEALTH-278397); WAKE-UP (Efficacy and safety of MRI-based thrombolysis in wake-up stroke: a randomised, double-blind, placebo-controlled trial – FP7-HEALTH-278276); BiomarCaRE (Biomarker for Cardiovascular Risk Assessment in Europe – FP7-HEALTH-278913)