Archive for September, 2015

22 September 2015

Publication RESOLVE

A recent paper by two partners of the RESOLVE consortium:


The Metabolic Syndrome can affect both glucose and lipid metabolism simultaneously, combining insulin resistance with high triglyceride levels and low HDL cholesterol. Therefore, to understand how Metabolic Syndrome develops, it is important to understand the interactions between glucose and lipid metabolism both in health and disease. However, how big the effect of these interactions are in everyday life is difficult to measure. This is especially true in the response to a meal, because both glucose and lipid concentrations are changing rapidly. In Sips et al, 2015, we use a mathematical model to get a new look at the interactions between glucose and fatty acids after simple meals. In this way, we get a new look at how glucose and fatty acids are affecting each other in healthy people.

Sips FL, Nyman E, Adiels M, Hilbers PA, Strålfors P, van Riel NA, Cedersund G.

Model-Based Quantification of the Systemic Interplay between Glucose and Fatty Acids in the Postprandial State. PLoS One. 2015 Sep 10;10(9):e0135665